Overview |
bsm-54702R |
KIFAP3 Monoclonal Antibody |
WB, FCM, IHC-P, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Synthetic Peptide within C-terminal human KIFAP3. |
Monoclonal |
7H10 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
22920 |
Q92845 |
Cytoplasm, Nucleus, Endoplasmic reticulum, Golgi apparatus, Cytoskeleton, Plasma membrane |
FLJ22818 antibody, KAP 3 antibody, KAP-3 antibody, KAP3 antibody, KIF3AP antibody, KIFA3_HUMAN antibody, Kifap3 antibody, Kinesin associated protein 3 antibody, Kinesin-associated protein 3 antibody, SMAP antibody, Smg GDS antibody, Smg GDS associated protein antibody, Smg GDS-associated protein antibody |
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |