Overview |
bsm-54343R |
Gephyrin (7A1) Monoclonal Antibody |
WB, FCM, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant protein within human Gephyrin aa 1-100. |
Monoclonal |
7A1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
10243 |
Q9NQX3 |
Cell membrane, Cytoskeleton |
Gephyrin; Molybdopterin adenylyltransferase; Domain G; Molybdopterin molybdenumtransferase; Domain E; MPT adenylyltransferase; MPT Mo-transferase; GPHN; GPH; KIAA1385 |
The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |