Overview |
bsm-54114R |
WDR5 (8G9) Monoclonal Antibody |
WB, FCM, IHC-P, IHC |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Synthetic peptide within human WDR5 aa 300 to the C-terminus |
Monoclonal |
8G9 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
11091 |
P61964 |
Nucleus |
WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; WDR5; BIG3; CFAP89; SWD3 |
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IHC |
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