Overview |
bsm-52808R |
PDIA6 (4C3) Monoclonal Antibody |
WB, FCM, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human PDIA6 between 300 to 500 amino acids |
Monoclonal |
4C3 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
10130 |
Q15084 |
Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, ER protein 5, ERp5, PDIA6 |
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936). |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |