Overview |
bsm-52786R |
Doublecortin (7C4) Monoclonal Antibody |
WB, FCM |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human Doublecortin aa 250 to the C-terminus |
Monoclonal |
7C4 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
1641 |
O43602 |
Neuronal migRation protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX |
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |