Overview |
bsm-52677R |
Stromal interaction molecule 1 (7C4) Monoclonal Antibody |
WB, IHC-P, IHC |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human Stromal interaction molecule 1 between 1-600 amino acids |
Monoclonal |
7C4 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
6786 |
Q13586 |
Stromal interaction molecule 1, STIM1 |
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC |
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