Delta Opioid Receptor (8A1) Monoclonal Antibody

Flow cytometric analysis of Sh-sy5y cells with Delta Opioid Receptor (8A1) Monoclonal Antibody (bsm-54334R) at a 1:50 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).

$Lane 1: HUVEC Cells; Lane 2: Rat brain; Probed with Delta Opioid Receptor (8A1) Monoclonal Antibody (bsm-52645R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: HUVEC Cells; Lane 2: Rat brain; Probed with Delta Opioid Receptor (8A1) Monoclonal Antibody (bsm-52645R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

Applications

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52645R
Product Name	Delta Opioid Receptor (8A1) Monoclonal Antibody
Applications	WB, FCM
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant protein within Human Delta Opioid Receptor aa 1-100
Clonality	Monoclonal
Clone #	8A1
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	4985
Swiss Prot	P41143
Synonyms	Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1
Background	G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Application Dilution
WB	1:300-5000
FCM	1:20-100