Overview |
bsm-52146R |
Cyclin E1(T77) (4G10) Monoclonal Antibody |
WB, IF(ICC) |
Human |
Specifications |
Unconjugated |
Rabbit |
Synthetic peptide derived from human Cyclin E1(T77), around 50-100aa (phospho T77). |
T77 |
Monoclonal |
4G10 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
898 |
P24864 |
Cyclin E1 phospho T77; p-Cyclin E1 phospho T77; Cyclin E1 Thr77; CCNE 1; CCNE;CCNE1;Cyclin E1 antibody Cyclin Es;Cyclin Et;CyclinE; G1/S specic cyclin E. |
Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |