PURB Monoclonal Antibody
Applications
Predicted Reactivity
Overview | |
Catalog # | bsm-51738M |
Product Name | PURB Monoclonal Antibody |
Applications | WB |
Predicted Reactivity | Human, Mouse |
Specifications | |
Conjugation | Unconjugated |
Host | Mouse |
Source | Recombinant human PURB. |
Clonality | Monoclonal |
Clone # | F4D9 |
Concentration | 0.5ug/ul |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 5814 |
Swiss Prot | Q96QR8 |
Subcellular location | Nucleus |
Synonyms | Pur beta; PURB_HUMAN; PURBETA; Purine rich element binding protein B; Purine-rich element-binding protein B; transcriptional activator protein Pur beta; Transcriptional activator protein Pur-beta. |
Background | Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs. |
Application Dilution | |
WB | =1:1000-4000, |