Overview |
bsm-51688M |
RAB7L1 Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Mouse |
Recombinant human RAB7L1. |
Monoclonal |
L6G11 |
IgG1 |
0.5ug/ul |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
8934 |
O14966 |
Cytoplasm, Cell membrane |
RAB29; DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; Ras related protein Rab 7L1; Ras-related protein Rab-7L1; Ras related protein Rab7L1. |
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. |
Application Dilution |
WB |
=1:500-2000, |