Overview |
bsm-51650M |
RAB14 Monoclonal Antibody |
WB |
Human, Mouse, Chicken |
Specifications |
Unconjugated |
Mouse |
Recombinant human RAB14. |
Monoclonal |
A12M1 |
0.5ug/ul |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
51552 |
P61106 |
Cytoplasm |
F protein binding protein 1; bA165P4.3; FBP; GTPase RAB 14; RAB-14; RAB14 member RAS oncogene family; RAB14_HUMAN; Ras related protein Rab 14; Ras-related protein Rab-14; RP11 165P4.4; Small GTP binding protein RAB14; FBP. |
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. |
Application Dilution |
WB |
=1:500-2000, |