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APEX1 (15C2) Monoclonal Antibody

Applications

  • WB
  • IHC-P

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-51448M
Product Name APEX1 (15C2) Monoclonal Antibody
Applications WB, IHC-P
Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Mouse
Source This APEX1 antibody is generated from a mouse immunized with a recombinant protein of human APEX1.
Clonality Monoclonal
Clone # 15C2
Isotype IgG1
Concentration 0.5ug/ul
Purification Purified by Protein G.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 328
Swiss Prot P27695
Synonyms APE; APX; APE1; APEN; APEX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1; APEX1
Background Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
Application Dilution
WB 1:300-5000
IHC-P 1:200-400