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BMI1 (2T6) Monoclonal Antibody

Applications

  • WB
  • IF

Reactivity

  • Human
Overview
Catalog # bsm-51082M
Product Name BMI1 (2T6) Monoclonal Antibody
Applications WB, IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.
Clonality Monoclonal
Clone # 2T6
Isotype IgG1
Concentration 0.5ug/ul
Purification Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 100532731, 648
Swiss Prot P35226
Background Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Application Dilution
WB 1:300-5000
IF