| Overview |
| bs-6840R-PE |
| IEX1 Polyclonal Antibody, PE Conjugated |
| WB |
| Rat |
| Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein |
| 85-156/156 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8870 |
| P46695 |
| Cell membrane |
| DIF2; IEX1; PRG1; DIF-2; GLY96; IEX-1; IEX-1L; Radiation-inducible immediate-early gene IEX-1; Differentiation-dependent gene 2 protein; Protein DIF-2; Immediate early protein GLY96; Immediate early response 3 protein; PACAP-responsive gene 1 protein; Protein PRG1; IER3 |
| May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. |
| Application Dilution |
| WB |
1:300-5000 |
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