Overview |
bs-6675R-Biotin |
KCNN4 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Rat |
Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit, Guinea Pig |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human KCNN4 |
325-427/427 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
3783 |
O15554 |
Cell membrane |
IK1; SK4; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1; Intermediate conductance calcium-activated potassium channel protein 4; SKCa 4; SKCa4; Putative Gardos channel; KCNN4 |
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |