Overview |
bs-5811R-PerCP-Cy5.5 |
NUAK2 Polyclonal Antibody, PerCP-Cy5.5 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse |
Rat, Dog, Cow, Rabbit |
Specifications |
PerCP-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human NUAK2 |
31-130/628 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
81788 |
Q9H093 |
Cytoplasm, Nucleus |
SNARK; NUAK family SNF1-like kinase 2; Omphalocele kinase 2; SNF1/AMP kinase-related kinase; NUAK2; OMPHK2 |
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |