Overview |
bs-55153R |
NFKB2 Polyclonal Antibody |
WB, IHC, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NFKB2 (NP_002493.3). |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
4791 |
Q00653 |
Cytoplasm, Nucleus |
CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52 |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
Application Dilution |
WB |
1:300-5000 |
IHC |
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IF |
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