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ADRBK1 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-55002R
Product Name ADRBK1 Polyclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 156
Swiss Prot P25098
Subcellular location Cytoplasm
Synonyms GRK2;ADRBK1;BARK1;BETA-ARK1
Background The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC