| Overview |
| bs-5443R-PE |
| ILK-1(Thr173) Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Rat |
| Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Thr173 |
| Thr173 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3611 |
| Q13418 |
| Cytoplasm, Cell membrane |
| P59; ILK-1; ILK-2; p59ILK; HEL-S-28; Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK; ILK1; ILK2 |
| Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. |
| Application Dilution |
| WB |
1:300-5000 |
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