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HOMER2 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Cow
  • Pig
  • Rabbit
Overview
Catalog # bs-4632R-Biotin
Product Name HOMER2 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Rat
Predicted Reactivity Human, Mouse, Cow, Pig, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HOMER2
Immunogen Range 301-354/354
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 9455
Swiss Prot Q9NSB8
Subcellular location Cytoplasm, Cell membrane, Extracellular matrix
Synonyms Cupidin; HOME2_HUMAN; HOMER 2; HOMER 2A; HOMER 2B; Homer homolog 2 Drosophila; Homer homolog 3; Homer neuronal immediate early gene 2; Homer protein homolog 2; Homer-2; Homer2; HOMER2A; HOMER2B; Vesl 2; Vesl2.
Background Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500