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MYPT1 (Thr853) Polyclonal Antibody, PerCP-Cy7 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-3288R-PerCP-Cy7
Product Name MYPT1 (Thr853) Polyclonal Antibody, PerCP-Cy7 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity This phosphorylation site is homologous to that of Thr852 in Mouse and Thr855 in Rat.
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation PerCP-Cy7
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human around the phosphorylation site of Thr853
Modification Site Thr853
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4659
Swiss Prot O14974
Subcellular location Cytoplasm
Synonyms MBS; M130; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A
Background Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200