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CRHR2 Polyclonal Antibody, Cy7 Conjugated

Applications

  • WB
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-2792R-Cy7
Product Name CRHR2 Polyclonal Antibody, Cy7 Conjugated
Applications WB, IF(IHC-F), IF(ICC)
Specificity This antibody may cross react with CRHR1.
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CRHR2
Immunogen Range 51-150/411
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1395
Swiss Prot Q13324
Subcellular location Cell membrane
Synonyms CRF2; CRFR2; CRF-RB; HM-CRF; Corticotropin-releasing factor receptor 2; CRF-R-2; CRF-R2; CRFR-2; Corticotropin-releasing hormone receptor 2; CRH-R-2; CRH-R2; CRHR2; CRF2R; CRH2R
Background G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Application Dilution
WB 1:300-5000
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200