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Nephrin (Tyr1217) Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-19199R
Product Name Nephrin (Tyr1217) Polyclonal Antibody
Applications WB, ELISA, IHC-P
Specificity This phosphorylation site is homologous to that of Tyr1232 in Mouse and Tyr1228 Rat.
Reactivity Human
Predicted Reactivity Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human Nephrin around the phosphorylation site of Tyr1217.
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 4868
Swiss Prot O60500
Subcellular location Cell membrane
Synonyms CNF; NPHN; nephrin; Renal glomerulus-specific cell adhesion receptor; NPHS1
Background Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400