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MGLUR5 Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Cow
  • Sheep
  • Horse
  • Chicken
  • Monkey
Overview
Catalog # bs-18801R-Cy3
Product Name MGLUR5 Polyclonal Antibody, Cy3 Conjugated
Applications WB, FCM
Reactivity Mouse, Rat
Predicted Reactivity Human, Cow, Sheep, Horse, Chicken, Monkey
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human MGLUR5
Immunogen Range 431-530/1212
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2915
Swiss Prot P41594
Subcellular location Cell membrane
Synonyms MGLUR5B; Glutamate receptor metabotropic 5; GPRC1E; GRM 5; GRM5; Metabotropic glutamate receptor 5; mGlu5; mGluR5; mGluR5a; mGluR5b; Metabotropic glutamate receptor 5 variant F; Metabotropic Glutamate Receptor 5b; Metabotropic glutamate receptor 5 variant G; Metabotropic glutamate receptor 5 variant H; PPP1R86; GRM5_HUMAN;
Background Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.
Application Dilution
WB 1:300-5000
FCM 1:20-100