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CANX/Calnexin Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Cow
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-1693R-PE
Product Name CANX/Calnexin Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Mouse, Rat
Predicted Reactivity Human, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CANX
Immunogen Range 501-592/592
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 821
Swiss Prot P27824
Subcellular location Cytoplasm, Cell membrane
Synonyms CNX; P90; IP90; Calnexin; Major histocompatibility complex class I antigen-binding protein p88; CANX
Background Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Application Dilution
WB 1:300-5000
FCM 1:20-100