Overview |
bs-16332R-BF488 |
GSDMC Polyclonal Antibody, AbBy Fluor® 488 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human |
Specifications |
AbBy Fluor® 488 |
Rabbit |
KLH conjugated synthetic peptide derived from human GSDMC |
1-100/508 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
56169 |
Q9BYG8 |
Cytoplasm |
Gasdermin C; Gasdermin-C; GSDMC; GSDMC_HUMAN; Melanoma derived leucine zipper, extra nuclear factor; Melanoma-derived leucine zipper-containing extranuclear factor; MLZE |
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |