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IFI16 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Mouse

Predicted Reactivity

  • Human
Overview
Catalog # bs-15548R-PE
Product Name IFI16 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Mouse
Predicted Reactivity Human
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IFI16
Immunogen Range 701-785/785
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3428
Swiss Prot Q16666
Subcellular location Cytoplasm, Nucleus
Synonyms I16; Gamma interferon inducible protein 16; Gamma-interferon-inducible protein i16; IF16_HUMAN; i204; NGIP1; interferon activated gene 204; Interferon gamma induced protein I 16; Interferon gamma inducible protein 16; Interferon-inducible myeloid dferentiation transcriptional activator; p204; PYHIN2.
Background IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Application Dilution
WB 1:300-5000