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GALNT10/GalNAc-T10 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Cow
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-13270R-PE
Product Name GALNT10/GalNAc-T10 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Mouse, Rat, Cow, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GALNT10/GalNAc-T10
Immunogen Range 151-250/603
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 55568
Subcellular location Cytoplasm, Cell membrane
Synonyms DKFZp586H0623; FLJ00205; FLJ11715; GalNAc T10; GalNAc transferase 10; GalNAc-T10; GalNAcT10; GALNT10; GLT10_HUMAN; Polypeptide GalNAc transferase 10; Polypeptide N-acetylgalactosaminyltransferase 10; pp GalNAc T10; pp GaNTase 10; pp-GaNTase 10; ppGalNAcT10; ppGaNTase 10; Protein UDP acetylgalactosaminyltransferase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10.
Background The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues of various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T10 (Polypeptide N-acetylgalactosaminyltransferase 10), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, is a 603 amino acid single-pass type II membrane protein that prefers Muc5Ac and EA2 peptide substrates. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T10 is widely expressed, with highest levels found in small intestine. There are four isoforms of GalNAc-T10 that are produced as a result of alternative splicing events.
Application Dilution
WB 1:300-5000

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