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PDGFRA (Tyr720) Polyclonal Antibody, AbBy Fluor® 555 Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Cow
  • Sheep
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-12595R-BF555
Product Name PDGFRA (Tyr720) Polyclonal Antibody, AbBy Fluor® 555 Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation AbBy Fluor® 555
Host Rabbit
Source KLH conjugated synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr720
Modification Site Tyr720
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5156
Swiss Prot P16234
Subcellular location Cell membrane
Synonyms PDGF Receptor alpha (phospho Y720); p-PDGF Receptor alpha (phospho Y720); Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF-R-alpha; PDGFR 2; PDGFR alpha; PDGFR2; PDGFRA; PDGFRA/BCR fusion; PGFRA_HUMAN; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; Platelet derived growth factor receptor; Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA.
Background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Application Dilution
WB 1:300-5000