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mGluR5 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Sheep
  • Chicken
Overview
Catalog # bs-1247R-PE
Product Name mGluR5 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Rat
Predicted Reactivity Human, Mouse, Dog, Sheep, Chicken
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse GRM5
Immunogen Range 201-300/1204
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 108071
Swiss Prot Q3UVX5
Subcellular location Cell membrane
Synonyms Glu5R; Gprc1e; mGluR5; mGluR5b; AI850523; 6430542K11Rik; Metabotropic glutamate receptor 5; Grm5
Background G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
Application Dilution
WB 1:300-5000