Overview |
bs-10771R-PE |
DHRS2 Polyclonal Antibody , PE Conjugated |
WB |
Human, Mouse, Rat |
Specifications |
PE |
Rabbit |
KLH conjugated synthetic peptide derived from human DHRS2 |
61-160/258 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10202 |
Q13268 |
Nucleus |
HEP27; SDR25C1; Dehydrogenase/reductase SDR family member 2, mitochondrial; Dicarbonyl reductase HEP27; Protein D; DHRS2 |
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. |
Application Dilution |
WB |
1:300-5000 |