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EGFRvIII Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Sheep
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-10627R
Product Name EGFRvIII Polyclonal Antibody
Applications WB, ELISA
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Sheep, Pig, Horse, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EGFRvIII
Immunogen Range 321-520/1210
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 1956
Swiss Prot P00533
Subcellular location Cell membrane
Synonyms GFRvIII; Epidermal growth factor receptor variant type _; epidermal growth factor receptor isoform a variant.
Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Application Dilution
WB 1:300-5000
ELISA 1:500-1000