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FGL2 Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-0315r-pe-100ul
Product Name FGL2 Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Mouse, Rat
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from rat FGL2
Immunogen Range 75-150/422
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 84586
Swiss Prot G3V7P2
Subcellular location Secreted
Synonyms Fibroleukin; Cytotoxic T-lymphocyte-specic protein; Fibrinogen-like protein 2; Fibrinogen like protein 2; Prothrombinase; Fibroleukin; pT49; T49; G3V7P2_RAT, Fibrinogen-like 2.
Background FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.
Application Dilution
WB 1:300-5000
FCM 1:20-100