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Isopimaric acid

Overview
Catalog # bs-83124c-5-mg
Product Name Isopimaric acid
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Terpenoid acid that activates BK (voltage-gated potassium) channels when used at 10 µM in HEK293 cells.1 Improves spatial and non-spatial memory in Alzheimer’s mouse model2,3, and significantly improves motor function in a rat spinal cord injury model4. Reduces hyperactivity of spontaneously active auditory networks, EC50=7.8 M.5
Description CAS Number: 5835-26-7

Chemical Name: (1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1- phenanthrenecarboxylic acid

Molecular weight: 302.45

Formula: C20H30O2

Solubility: DMSO (40 mg/ml)

Physical Properties: White solid

Purity: 98% by GC, TLC NMR (conforms)