Locostatin
| Overview | |
| Catalog # | bs-83112c-5-mg |
| Product Name | Locostatin |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Inhibits cell migration by disrupting the interaction between Raf kinase inhibitor protein (RKIP) and Raf-1 kinase.1 Locostatin covalently binds to His86 of RKIP and also disrupts its interaction with G protein-coupled receptor kinase 2.2 Effectively inhibits cytokine release by human lymphocytes.3 Alleviates CCl4-induced liver fibrosis in a mouse model.4 A useful probe to explore the complex functions of RKIP in cell physiology.5 |
| Description | CAS Number: 133812-16-5 Chemical Name: (4S)-3-[(E)-But-2-enoyl]-4-benzyl-2-oxazolidinone Molecular weight: 245.28 Formula: C14H15O3 Solubility: DMSO (60 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |
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