HET0016
| Overview | |
| Catalog # | bs-83104c-5-mg |
| Product Name | HET0016 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | HET0016 (339068-25-6) inhibits 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis via omega oxidation of arachidonic acid mediated by CYP4A and 4F (IC50=8.9 nM in human renal microsomes).1 It displays neuroprotective effects in a rat model of traumatic brain injury via inhibition of neuronal pyroptosis.2 HET0016 attenuates cerebral ischemia-reperfusion injury3 as well as oxidative injury and peripheral nerve damage in type-2 diabetic mice4. It alleviates myocardial oxidative stress5 and restores endothelial function suggesting therapeutic potential in obesity-associated vascular disease6. |
| Description | CAS Number: 339068-25-6 Chemical Name: N-Hydroxy-N’-(4-butyl-2-methylphenyl)formamidine Molecular weight: 206.29 Formula: C12H18N2O Solubility: DMSO (20 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms) |
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