GKT-137831
| Overview | |
| Catalog # | bs-83080c-5-mg |
| Product Name | GKT-137831 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6 |
| Description | CAS Number: 1218942-37-0 Chemical Name: 2-(2-Chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione Molecular weight: 394.85 Formula: C21H19ClN4O2 Solubility: DMSO (65 mg/ml) Physical Properties: Pale-yellow solid Purity: 98% by TLC NMR (Conforms) |
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