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Deferasirox

Overview
Catalog # bs-83066c-10-mg
Product Name Deferasirox
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological patients.1,2 It has been shown to potent inhibitor of JumonjiC Domain-Containing Histone Demethylases (IC50’s = KDM4A(JMJD2A) 4.76 µM, KDM5A(JARID1A) 5.00 µM, KDM6B(JMJD3) 3.95 µM).3 Deferasirox has also been investigated as a potential anticancer agent.4-6
Description CAS Number: 201530-41-8

Chemical Name: 4-[3,5-bis(2-Hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid

Molecular weight: 373.36

Formula: C21H15N3O4

Solubility: DMSO (10 mg/ml)

Physical Properties: Off-white to white solid

Purity: >98% by HPLC NMR (Conforms)