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Darunavir

Overview
Catalog # bs-83063c-10-mg
Product Name Darunavir
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Darunavir is a very potent (IC50 = 3 nM against lab HIV-1 strains and clinical isolates) HIV-1 protease inhibitor that is in clinical use.1,2 Also potent against multi-PI-resistant HIV-1 strains from patient samples. Darunavir has been investigated as a potential anti-SARS-CoV2 therapeutic with mixed results.3-6
Description CAS Number: 206361-99-1

Chemical Name: [(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

Molecular weight: 547.67

Formula: C27H37N3O7S

Solubility: DMSO (>25 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC NMR (conforms)