NDI-091143
| Overview | |
| Catalog # | bs-83046c-5-mg |
| Product Name | NDI-091143 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent (IC50 = 2.1 nM ADP-Glo assay; 4.8 nM Oxaloacetate coupled enzyme assay) allosteric inhibitor of ATP-citrate lyase.1 NDI-091143 suppressed growth and clonogenic ability in thyroid cancer cell lines FTC-133 and 8505C.2 It also synergistically potentiated the cytotoxicity of sorafenib.2 |
| Description | CAS Number: 2375840-87-0 Chemical Name: Methyl 3-Chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate Molecular weight: 453.84 Formula: C20H14ClF2NO5S Solubility: DMSO (>50 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms) |
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