NVP-BGJ398
| Overview | |
| Catalog # | bs-83033c-10-mg |
| Product Name | NVP-BGJ398 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | NVP-BGJ398 is a potent and selective pan-FGFR inhibitor (IC50 = 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively).1 It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.2 |
| Description | CAS Number: 872511-34-7 Chemical Name: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylurea Molecular weight: 560.48 Formula: C26H31Cl2N7O3 Solubility: DMSO (5 mg/ml) Physical Properties: White solid Purity: 99% by HPLC NMR (Conforms) |
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