Ipatasertib
| Overview | |
| Catalog # | bs-83006c-5-mg |
| Product Name | Ipatasertib |
| Specifications | |
| Storage Buffer | Beige solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Ipatasertib is a selective (against a panel of 230 kinases) and potent pan-Akt inhibitor (IC50s: Akt1 = 5 nM, Akt2 = 18 nM, Akt3 = 8 nM).1 It displayed efficacy in xenograft models of prostate, breast, ovarian, colorectal, non-small cell lung, glioblastoma, and melanoma cancers.2 In clinical trials. |
| Description | CAS Number: 1001264-89-6 Chemical Name: (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-yla,ino)propan-1-one Molecular weight: 458.00 Formula: C24H32ClN5O2 Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml) Physical Properties: Off-white of pale pink solid Purity: 98% by HPLC NMR (Conforms) |
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