CBR-470-1
| Overview | |
| Catalog # | bs-82986c-5-mg |
| Product Name | CBR-470-1 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Activator of NRF2 signaling (EC50 ~ 1 µM cellular ARE-LUC assay).1 It inhibits phosphoglycerate kinase 1 leading to a build-up of methylglyoxal which inactivates KEAP1. It protected SH-SY5Y neuronal cells from MPP+ induced oxidative injury via activation of NRF2 signaling.2 |
| Description | CAS Number: 2416095-06-0 Chemical Name: trans-4-(4-Chlorophenyl)sulfonyl-N-(2-methylpropyl)-1,1-dioxothiolan-3-amine Molecular weight: 365.89 Formula: C14H20ClNO4S2 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms) |
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