SR9243

Overview
Catalog #	bs-82932c-5-mg
Product Name	SR9243
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	SR9243 is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.1 Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50 = 18 nM). SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.
Description	CAS Number: 1613028-81-1 Chemical Name: N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3’-(methylsulfonyl)[1,1’-biphenyl]-4-yl]methyl]-benzenesulfonamide Molecular weight: 626.62 Formula: C31H32BrNO4S2 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms)