Mitoguazone · 2HCl
| Overview | |
| Catalog # | bs-82916c-10-mg |
| Product Name | Mitoguazone · 2HCl |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3 Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.6 |
| Description | CAS Number: 31959-87-2 Chemical Name: Methylglyoxal bis(guanylhydrazone) dihydrochloride Molecular weight: 257.13 Formula: C5H12N8 · 2HCl Solubility: water (>25 mg/ml) DMSO (?) Physical Properties: White solid Purity: 98% by HPLC, NMR (Confirms) |
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