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MDL29,951

Overview
Catalog # bs-82903c-5-mg
Product Name MDL29,951
Specifications
Storage Buffer White solid
Storage Condition RT
Target
Product Information MDL29,951 is a new, highly specific, small molecule activator of GPR171 that has been shown to be active in intact cells1. The ability to specifically activate GPR17 allows for the study of the exact role GPR17 plays in the maturation of oligodendrocytes and may lead to a therapeutic strategy to promote myelin repair. Antagonist for the strychnine-insensitive glycine binding site of the NMDA receptor (IC50 = 170 nM).2
Description CAS Number: 130798-51-5

Chemical Name: 3-(2-Carboxy-4,6-dichloroindol-3-yl)propionic acid

Molecular weight: 302.11

Formula: C12H9Cl2NO4

Solubility: DMSO (15 mg/ml) Ethanol (10 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by TLC (10% MeOH/methylene chloride + 0.5% HOAc) NMR: (Conforms)