Mitapivat

Overview
Catalog #	bs-82875c-5-mg
Product Name	Mitapivat
Specifications
Storage Buffer	White to off-white solid
Storage Condition	-20°C
Target
Product Information	Potent (AC50 = 29 nM PKR; 37 nM PKM2; 33 nM PKL) allosteric activator of pyruvate kinase.1 In clinical use for the treatment of hemolytic anemia2 and a potential agent for the treatment for ß-thalassemia3 and sickle cell anemia4.
Description	CAS Number: 1260075-17-9 Chemical Name: N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide Molecular weight: 450.56 Formula: C24H26N4O3S Solubility: DMSO (>50 mg/ml) Physical Properties: Beige solid Purity: 99% by HPLC NMR (Conforms)