Sulfopin
Overview | |
Catalog # | bs-82869c-5-mg |
Product Name | Sulfopin |
Specifications | |
Storage Buffer | Pale yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1) (Ki = 17 nM).1 Although it displayed little to no cytotoxicity against a panel of 300 cancer cell lines, it had a significant impact on cancer cell growth after prolonged treatment. It suppressed MYCN-driven neuroblastoma initiation and the growth and survival of primary neuroblastoma tumor cell transplants in zebrafish. |
Description | CAS Number: 2451481-08-4 Chemical Name: 2-Chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide Molecular weight: 281.8 Formula: C11H20ClNO3S Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |