Autogramin-2

Overview
Catalog #	bs-82865c-5-mg
Product Name	Autogramin-2
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Autogramin-2 is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A). Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.
Description	CAS Number: 2375541-45-8 Chemical Name: t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate Molecular weight: 417.53 Formula: C21H27N3O4S Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms)