TH257

Overview
Catalog #	bs-82861c-5-mg
Product Name	TH257
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	TH257 is a potent (IC50’s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.
Description	CAS Number: 2244678-29-1 Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide Molecular weight: 422.54 Formula: C24H26N2O3S Solubility: DMSO (25 mg/ml) Physical Properties: White to off-white glassy solid Purity: >98% by HPLC NMR (Conforms)